Abstract. Syariah stock return in property and real estate industry shows a fluctuate development which tend to decrease, but this condition does not in line with the progress in property and real estate sector. Therefore, we need to analyze the factors that are influential towards syariah stock return in order to prevent that trend to continue so that the property and real estate sub-sector company will no longer experience a loss. This research aims to find out about how is the development of DER, DPR, Asset Growth, anf Syariah Stock Return in property and real estate sub-sector company registered in Indonesian Syariah Stock Index (ISSI), how is the effect of DER, DPR, and Asset Growth towards Syariah Stock Return in property and real estate sub-sector company registered in Indonesian Syariah Stock Index (ISSI) simultaneously and partially. The population of this research are as many as 40 property and real estate sub-sector companies registered in ISSI during 2013-2017 period, and the sample used are as many as 7 property and real estate sub-sector companies registered in ISSI and fulfilled some of the specified criterias. The method used in this research is quantitative. The source of data used is secondary data. The instrument used to analyze the data is SPSS software.  The result of this research shows that the development  of DER, DPR, Assets Growth, and Syariah Stock Return experience a fluctuation in which the development of DER from 2013-2017 decrease each year, differ from DPR and Assets Growth which increase and decrease in a fluctuate manner. Also differ from syariah stock return which also experience a fluctuated development but tend to decrease. Analysis of simultaneous variable X1,  X2  and X3are simultaneously influential towards variable Y. Its determination coeffiecient (R square) shows a number of 0,432 or 43,2%. This number means that as much as 43,2% of dependent variable change can be explained with determinant variable in model, while the residue of 56,8% is affected by other variable outside the model. The analysis of partial variable resulted in a value of statistic X1 (DER) positively and significantly influential towards Y, while   X2 and X3are not influential towards variable Y. Abstrak. Return saham syariah pada industri property dan real estate menunjukkan perkembangan yang fluktuatif cenderung menurun, tetapi kondisi tersebut tidak selaras dengan kemajuan yang dialami oleh sektor property dan real estate. Maka dari itu kita perlu menganalisis faktor-faktor yang dapat mempengaruhi return saham syariah agar tren tersebut tidak berlanjut dan perusahaan sub-sektor property dan real estate akhirnya tidak akan mengalami kerugian. Tujuan dari penelitian ini adalah untuk mengetahui bagaimana perkembangan DER, DPR, Assets Growth, dan Return Saham Syariah pada perusahaan sub-sektor property dan real estate yang terdaftar di Indeks Saham Syariah Indonesia (ISSI), bagaimana pengaruh DER, DPR dan Assets Growth terhadap Return Saham Syariah pada perusahaan sub-sektor property dan real estate yang terdaftar di Indeks Saham Syariah Indonesia (ISSI) secara simultan, dan secara parsial. Populasi penelitian ini adalah sebanyak 40 perusahaan sub-sektor property dan real estate yang terdaftar di ISSI pada tahun 2013-2017 dan sampel dari penelitian ini adalah sebanyak 7 perusahaan sub-sektor property dan real estate yang tercatat di ISSI dan memenuhi beberapa kriteria yang ditetapkan. Metode penelitian yang digunakan adalah pendekatan kuantitatif. Sumber data yang digunakan data sekunder. Alat analisis data yang digunakan adalah software SPSS. Hasil Penelitian diperoleh bahwa perkembangan DER, DPR, Assets Growth dan Return Saham Syariah mengalami fluktuasi yaitu perkembangan DER dari tahun 2013-2017 mengalami penurunan dari tahun ke tahun, berbeda dengan DPR dan Assets Growth yang mengalami kenaikan dan penurunan secara fluktuatif. Berbeda juga dengan return saham syariah yang mengalami perkembangan yang fluktuatif tetapi cenderung menurun. Analisis simultan variabel X1,  X2  dan X3 secara bersama-sama (simultan) berpengaruh terhadap variabel Y. Koefisien determinasinya (R Square) menunjukkan nilai sebesar 0,432  atau 43,2%%. Nilai ini berarti bahwa sebesar 43,2% perubahan variabel dependen dapat dijelaskan oleh variabel penentu dalam model, sedangkan sisanya 56,8% dipengaruhi oleh variabel lain di luar model. Analisis parsial variabel menghasilkan nilai statistik X1 (DER) berpengaruh positif dan signifikan terhadap Y, sedangkan X2 dan X3 tidak berpengaruh terhadap variabel Y.Kata Kunci: DER, DPR, Assets Growth, Return Saham Syariah, Industri, Indeks Saham Syariah Indonesia (ISSI)Abstract. Syariah stock return in property and real estate industry shows a fluctuate development which tend to decrease, but this condition does not in line with the progress in property and real estate sector. Therefore, we need to analyze the factors that are influential towards syariah stock return in order to prevent that trend to continue so that the property and real estate sub-sector company will no longer experience a loss. This research aims to find out about how is the development of DER, DPR, Asset Growth, anf Syariah Stock Return in property and real estate sub-sector company registered in Indonesian Syariah Stock Index (ISSI), how is the effect of DER, DPR, and Asset Growth towards Syariah Stock Return in property and real estate sub-sector company registered in Indonesian Syariah Stock Index (ISSI) simultaneously and partially. The population of this research are as many as 40 property and real estate sub-sector companies registered in ISSI during 2013-2017 period, and the sample used are as many as 7 property and real estate sub-sector companies registered in ISSI and fulfilled some of the specified criterias. The method used in this research is quantitative. The source of data used is secondary data. The instrument used to analyze the data is SPSS software.  The result of this research shows that the development  of DER, DPR, Assets Growth, and Syariah Stock Return experience a fluctuation in which the development of DER from 2013-2017 decrease each year, differ from DPR and Assets Growth which increase and decrease in a fluctuate manner. Also differ from syariah stock return which also experience a fluctuated development but tend to decrease. Analysis of simultaneous variable X1,  X2  and X3are simultaneously influential towards variable Y. Its determination coeffiecient (R square) shows a number of 0,432 or 43,2%. This number means that as much as 43,2% of dependent variable change can be explained with determinant variable in model, while the residue of 56,8% is affected by other variable outside the model. The analysis of partial variable resulted in a value of statistic X1 (DER) positively and significantly influential towards Y, while   X2 and X3are not influential towards variable Y.