| dc.contributor |
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| dc.contributor |
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| dc.creator |
Faridatussaadah, Siti Nur |
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| dc.creator |
Lukmayani, Yani |
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| dc.creator |
Dasuki, Undang A |
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| dc.date |
2016-02-20 |
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| dc.identifier |
http://karyailmiah.unisba.ac.id/index.php/farmasi/article/view/3100 |
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| dc.description |
The research describes Isolation and identification of flavonoid compound from bowl plant leaves (Polyscias scutellarium (Burm.f.) Fosb). The result of fitochemistry shows there is a category of alkaloid, flavonoid, saponin, triterpenoid/steroid, and polifenolat. The extraction is done by using maserasi method, it results in thick extract as many as 323,96 gram with extract bath of 32,396%. The fractsination id done using liquid-liquid extraction methode with n-heksan solvent, estate ethyl, and water. Subfracsination is done for asetate ethyl fraction with UV-Visible chromatography with elusion system. Purification process is done using preparative KLT with silent phase of silica gel GF254 and movement phase of n-heksan: acetate ethyl (6:4) up to it results isolate. Ioslate purification and characterization is tested ultra-purple- visible spectrophotometry. Characterization is then done using gestalt reagent of NaOH, AlCl3, dan AlCl3/HCl. The result of characterization concludes that isolate of bowl plant leaves (Plyscias scutellarium (Burm.f.) Fosb is flavonoid compound of auron category. |
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| dc.description |
Telah dilakukan penelitian mengenai isolasi dan identifikasi senyawa flavonoid dari daun mangkokan (Polyscias scutellarium (Burm.f.) Fosb. Hasil dari penapisan fitokimia menunjukkan adanya golongan alkaloid, flavonoid, saponin, triterpenoid/steroid, dan polifenolat. Ekstraksi dilakukan dengan metode maserasi menghasilkan ekstrak kental sebanyak 323,96 gram dengan rendemen ekstrak sebesar 32,396%. Fraksinasi dilakukan dengan metode ekstraksi cair-cair (ECC) menggunakan pelarut n-heksan, etil asetat dan air. Terhadap fraksi etil asetat dilakukan subfraksinasi dengan kromatografi cair vakum (KCV) dengan sistem elusi landaian. Pemurnian menggunakan KLT preparatif dengan fase diam silika gel GF254 dan fase gerak n-heksan : etil asetat (6:4) hingga diperoleh isolat. Terhadap isolat dilakukan uji kemurnian dan karakterisasi dengan spektrofotometri ultra ungu - sinar tampak. Karakterisasi dilanjutkan dengan menggunakan pereaksi geser NaOH, AlCl3, dan AlCl3/HCl. Dari hasil karakterisasi dapat disimpulkan bahwa isolat dari daun mangkokan (Plyscias scutellarium (Burm.f.) Fosb adalah senyawa flavonoid golongan auron. |
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| dc.format |
application/pdf |
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| dc.language |
ind |
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| dc.publisher |
Universitas Islam Bandung |
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| dc.relation |
http://karyailmiah.unisba.ac.id/index.php/farmasi/article/view/3100/pdf |
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| dc.source |
Prosiding Farmasi; Vol 2, No 1, Prosiding Farmasi (Februari, 2016); 141-150 |
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| dc.source |
Prosiding Farmasi; Vol 2, No 1, Prosiding Farmasi (Februari, 2016); 141-150 |
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| dc.source |
2460-6472 |
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| dc.subject |
Proceedings of Pharmacy |
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| dc.subject |
Isolation, flavonoid, auron, bowl plant. |
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| dc.subject |
Farmasi Bahan Alam |
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| dc.subject |
Isolasi, Flavonoid, Auron, Mangkokan |
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| dc.title |
Isolation and identification of flavonoid compound from bowl plant leaves (Polyscias scutellarium (Burm.f.) Fosb). |
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| dc.title |
Isolasi dan Identifikasi Senyawa Flavonoid dari Daun Mangkokan (Polyscias scutellarium (Burm.f.) Fosb) |
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| dc.type |
info:eu-repo/semantics/article |
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| dc.type |
info:eu-repo/semantics/publishedVersion |
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| dc.type |
Peer-reviewed Article |
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| dc.type |
Quantitative |
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| dc.type |
Eksperimen Laboratorium |
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