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Comparison Between The Effects of Leaf Litter of Chinese Petai (Leucaena leucocephala) and Honey on The Wound Healing Process in Mice

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dc.contributor
dc.contributor
dc.creator kholilah, Milke
dc.creator Indriyanti, R. Anita
dc.creator Budiman, Budiman
dc.date 2017-08-10
dc.date.accessioned 2019-09-13T05:58:10Z
dc.date.available 2019-09-13T05:58:10Z
dc.identifier http://karyailmiah.unisba.ac.id/index.php/dokter/article/view/8202
dc.identifier.uri http://hdl.handle.net/123456789/25929
dc.description Leaf of Chinese Petai and honey is some of the plants and drink that can be used in the treatment of wounds. They contained in Chinese Petai leaf as flavonoids and tannins have activity as antioxidants, catalase, inhibits the formation of mediators and enzymes that cause inflammation. These activities helped the wound healing process. This research is an experimental laboratory with complete randomized design method where 27 male Swiss Webster rats were divided into 3 groups. Positive control (povidone iodine 10%) and 2 treatment groups (group II and III) were each given honey and litter leaf of chinese petai topically. Measurements were made during 14 days beginning one day after the incision on the back area with a length 1,5 cm. The data was analysed with Oneway Anova method and Post Hoc Tukey test which showed not significant difference in mean wound healing between groups of  povidone iodine 10%, honey and Chinese Petai leaf (p>0,05). The result of the study showed that povidone iodine 10%, honey and Chinese Petai leaf given the effect to wound healing incision but there is no difference in the rate of wound healing.
dc.description Daun Petai Cina dan madu merupakan salah satu tanaman dan minuman yang dapat digunakan dalam pengobatan luka. Kandungan yang terdapat di dalam daun Petai Cina dan madu seperti flavonoid dan tanin memiliki aktivitas sebagai anti oksidan, katalase, menghambat pembentukan mediator-mediator dan enzim yang menyebabkan terjadinya inflamasi. Aktivitas-aktivitas inilah yang nantinya akan berperan dalam membantu penyembuhan luka. Penelitian ini bersifat eksperimental laboratoris dengan metode rancang acak lengkap terhadap 27 mencit jantan galur Swiss Webster yang terbagi dalam 3 kelompok. Kelompok kontrol positif (povidone iodine 10%) dan 2 kelompok perlakuan (kelompok II dan III) yang masing-masing diberikan madu dan lumatan daun Petai Cina secara topikal. Pengukuran dilakukan selama 14 hari berturut-turut yang dimulai satu hari setelah pemberian perlakuan berupa insisi daerah punggung dengan panjang 1,5 cm. Data di analisis dengan uji Oneway Anova dan Post Hoc Tukey menunjukan tidak terdapat perbedaan signifikan rata-rata penyembuhan luka antar kelompok povidone iodine 10%, madu dan lumatan daun Petai Cina  (p>0,05). Hasil penelitian menunjukan bahwa pemberian povidone iodine 10%, madu dan lumatan daun Petai Cina memberikan pengaruh terhadap penyembuhan luka insisi tetapi tidak terdapat perbedaan dalam waktu kecepatan penyembuhan luka.
dc.format application/pdf
dc.language ind
dc.publisher Universitas Islam Bandung
dc.relation http://karyailmiah.unisba.ac.id/index.php/dokter/article/view/8202/pdf
dc.rights Copyright (c) 2017 Prosiding Pendidikan Dokter
dc.source Prosiding Pendidikan Dokter; Vol 3, No 1, Prosiding Pendidikan Dokter (Agustus, 2017); 375-386
dc.source Prosiding Pendidikan Dokter; Vol 3, No 1, Prosiding Pendidikan Dokter (Agustus, 2017); 375-386
dc.source 2460-657X
dc.subject Medical Study
dc.subject Chinese Petai leaf, honey, wound.
dc.subject Kedokteran
dc.subject Daun Petai Cina, madu, luka
dc.title Comparison Between The Effects of Leaf Litter of Chinese Petai (Leucaena leucocephala) and Honey on The Wound Healing Process in Mice
dc.title Perbandingan antara efek lumatan daun petai cina (leucaena leucocephala) dan madu terhadap proses penyembuhan luka pada mencit
dc.type info:eu-repo/semantics/article
dc.type info:eu-repo/semantics/publishedVersion
dc.type Peer-reviewed Article
dc.type Quantitative
dc.type kuantitatif


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