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Uji Aktivitas Antifungi Ekstrak Etanol Daun Ceremai (Phyllanthus Acidus (L.) Skeels) terhadap Candida Albicans

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dc.contributor Fakultas Matematika dan Ilmu Pengetahuan Alam
dc.creator Muttaqin, Deazs Miftah
dc.creator Suwendar, Suwendar
dc.creator Choesrina, Ratu
dc.date 2019-01-25
dc.identifier http://karyailmiah.unisba.ac.id/index.php/farmasi/article/view/14499
dc.description Abstract. The use of plants in the treatment of various diseases has been widely carried out, one of which caused by fungi. One of fungus species which may cause various types of infections is Candida albicans. Based on previous research, gooseberry plant contains flavonoid, tannin and saponin. In this study a test was conducted to determine the antifungal activity of the gooseberry leaf ethanol extract using the diffusion method, minimum inhibition concentration (MIC) level, using using agar dilution method, and equality of gooseberry leaf extract with standard. The results obtained from the study, namely, the ethanol extract of the gooseberry leaf has antifungal activity at a concentration of 12.5-25% with an average inhibition diameter of 5.8-7.93 mm, the MIC value of the obtained gooseberry ethanol extract is 9%, and the value of equality of ketoconazole against the fungi of Candida albicans is 1 mg of ethanol extract of the ceremai setra leaves with 1,052 x 10-4 mg of ketoconazole.Keywords : gooseberry leaf , candida albicans, ketoconazole,antifungalAbstrak. Penggunaan tanaman dalam pengobatan berbagai penyakit telah banyak dilakukan, salah satunya yaitu penyakit yang disebabkan oleh fungi. Salah satu spesies jamur yang dapat menyebabkan berbagai jenis infeksi adalah Candida albicans. Bedarsarkan penelitian sebelumnya, tanaman ceremai mengandung senyawa kimia flavonoid, tannin, dan saponin. Pada penelitian ini dilakukan pengujian untuk mengetahui aktivitas antifungi ekstrak etanol daun ceremai dengan menggunakan metode difusi, nilai konsentrasi hambat minimum (KHM) menggunakan metode pengenceran agar, serta kesetaraan ekstrak daun cemremai dengan pembanding. Hasil yang diperoleh dari pengujian yaitu, ekstrak etanol daun ceremai memiliki aktivitas antifungi pada konsentrasi 12,5-25% dengan rata-rata diameter hambat 5,8-7,93 mm, nilai KHM ekstrak etanol daun ceremai yang diperoleh adalah 9%, serta nilai kesetaraan ketokonazol terhadap fungi Candida albicans adalah 1 mg ekstrak etanol daun ceremai setra dengan 1,052 x 10-4 mg ketokonazol.Kata Kunci : Daun ceremai , candida albicans, ketokonazol,antifungi
dc.format application/pdf
dc.language eng
dc.publisher Universitas Islam Bandung
dc.relation http://karyailmiah.unisba.ac.id/index.php/farmasi/article/view/14499/pdf
dc.rights Copyright (c) 2019 Prosiding Farmasi
dc.source Prosiding Farmasi; Vol 5, No 1, Prosiding Farmasi (Februari, 2019); 42-48
dc.source Prosiding Farmasi; Vol 5, No 1, Prosiding Farmasi (Februari, 2019); 42-48
dc.source 2460-6472
dc.subject Farmasi
dc.subject Daun ceremai , candida albicans, ketokonazol,antifungi
dc.title Uji Aktivitas Antifungi Ekstrak Etanol Daun Ceremai (Phyllanthus Acidus (L.) Skeels) terhadap Candida Albicans
dc.type info:eu-repo/semantics/article
dc.type info:eu-repo/semantics/publishedVersion
dc.type Peer-reviewed Article
dc.type kuantitatif


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